Institute for Systems Biology focuses on some of the most pressing issues in human health, including cancer and brain health. ISB President and Professor James Heath, PhD, is a PICI investigator who bridges cutting-edge technology and immune system biology. He builds new technologies to investigate how individual patients’ immune systems respond to therapeutic interventions including vaccines, checkpoint blockade and CAR-T cell therapy. He collaborates with PICI in high-need areas, pushing progress in glioblastoma and brain tumor research. James Heath, PhD | Investigator Related Research Focus Tumor Antigen Discovery: Targeting Cancer Research Project Tumor Neoantigen Selection Alliance (TESLA) Announcement Note from PICI’s President and CEO Jeff Bluestone: Introducing Our New Brand Clinical Trial The PORTER Trial Our Impact Informatics Accelerates the PRINCE Pancreatic Cancer Clinical Trial Our Impact PICI BioTrust Decodes Triple Negative Breast Cancer in TRIBUTE Collaboration Our Impact Improve Life After Cancer: Addressing Autoimmunity Partner Highlight Nonprofits Join Forces for a Cure: Cancer Research Institute Research Update Where Cancer-killing T-cells Come From