Summary of Invention PICI investigators at Stanford Medicine studying circular RNA (circRNA) as a vehicle for ectopic gene expression unexpectedly discovered that circRNA is a potent immunostimulant that could be used as an adjuvant in vaccine settings and could also be used to deliver drugs to patients. International Publication Number WO 2017/222911 A1 (.pdf) International Application Filing Date 06.15.17 Inventors Howard Chang, MD, PhD Bali Pulendran, PhD Grace Chen, PhD Institution Stanford Medicine Category Vaccines