Howard Y. Chang, MD, PhD Principal Investigator, Professor of Dermatology Biography Howard Y. Chang M.D., Ph.D. is Director of the Center for Personal Dynamic Regulomes and Professor of Dermatology at Stanford University School of Medicine. Chang earned a Ph.D. in Biology from MIT, M.D. from Harvard Medical School, and completed Dermatology residency and postdoctoral training at Stanford University. His research addresses how large sets of genes are turned on or off together, which is important in normal development, cancer, and aging. Chang discovered a new class of genes, termed long noncoding RNAs, can control gene activity throughout the genome, illuminating a new layer of biological regulation. He has invented new methods for defining the shapes of RNA and DNA genome-wide. The long-term goal of his research is to decipher the regulatory information in the genome to benefit human health. Dr. Chang’s honors include the Paul Marks Prize for Cancer Research, Judson Daland Prize of the American Philosophical Society, Howard Hughes Medical Institute Early Career Scientist, the Vilcek Prize for Creative Promise, Alfred Marchionini Research Prize, American Cancer Society Research Scholar Award, Damon Runyon Scholar Award, and elected membership to the American Society for Clinical Investigation and Academia Sinica. His work was honored by the journal Cell as a Landmark paper over the last 40 years and by Science as “Insight of the decade”. Education & Training 1994: Harvard, Cambridge, MA, AB, Biochemistry 1998: MIT, Cambridge, MA, PhD, Biology 2000: Harvard Medical School, Boston, MA, MD 2001: Santa Clara Valley Medical Center, San Jose, CA, Internship 2003: Stanford University School of Medicine, Stanford, CA, Residency 2004: Dermatology, American Board of Dermatology, Board Certification 2004: Stanford University School of Medicine, Stanford, CA,Fellowship Awards & Honors 2015: Paul Marks Prize for Cancer Research, Memorial Sloan Kettering Cancer Institute 2014: Judson Daland Prize, American Philosophical Society 2012: Montagna Lecture, Society for Investigative Dermatology; Salvador E. Luria Lecture, Massachusetts Institute of Technology 2011: Alfred Marchionini Research Prize, Alfred Marchionini Foundation 2010: CE.R.I.E.S. Award, Chanel Research and Technology 2009: Early Career Scientist, Howard Hughes Medical Institute; Elected Member, American Society for Clinical Investigation; Senior Scholar Award in Aging, Ellison Medical Foundation; Vilcek Prize for Creative Promise, Vilcek Foundation 2008: New Faculty Award, California Institute for Regenerative Medicine 2007: Research Scholar Award, American Cancer Society 2006: Scholar Award, Damon Runyon Cancer Research Foundation 2004: Clinical Scientist Career Development Award (K08), NIH; Physician-Scientist Career Development Award, Dermatology Foundation 2003: Young Investigator Award, American Academy of Dermatology