Taha Merghoub is an Assistant Attending Lab Member at Memorial Sloan Kettering Cancer Center. He researches the pathogenesis and treatment of melanoma, and develops tools to study melanoma. The majority of Merghoub’s research uses mice to test the interactions of melanoma with various components. He is developing mouse models of melanoma that mimic different stages of human disease clinically, pathologically and genetically, later evaluating new immunotherapies at different stages of tumor progression in experiments. He is also generating mice whose immune cells are genetically labeled with fluorescent proteins that allow him to track the in vivo behavior of specific immune cells in a melanoma-bearing host. Finally, he is studying tumorigenesis in FAP deficient mice to determine how FAP protects against tumor formation with melanoma-prone mice developed in our lab, examining different pathways for regulation of cell growth, including ras-Braf-mek, INK4a, p53 and Pten/Akt.