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Lawrence Fong, MD

Lawrence Fong, MD

Genitourinary Cancer Specialist and Professor of Medicine

Biography

Lawrence Fong is a specialist in genitourinary cancer at the UCSF Medical Center and an associate professor of medicine at the University of California, San Francisco. Fong is particularly interested in tumor immunology and developing immune-based treatments of cancer. His lab is focused on structure function studies of nuclear receptors and transcription control proteins in stem cells. He uses biochemical and biophysical methods to evaluate protein complexes. His lab determined the first three-dimensional structure for any nuclear receptor and published papers on the thyroid hormone receptor, androgen receptor and glucocorticoid receptor, as well as on LRH-1, SF-1 and Dax-1 receptors, and developed bait-affinity expression for making the first complex of a nuclear receptor with its corepressor. Research on androgen receptor interactions with peptides and small molecules helped define the specificity of the AF2 site and led to the discovery of a new protein binding site on the androgen receptor hormone binding domain. Fong’s lab is known for determining structures of important protein molecules and assemblies, and relating structures to the mechanisms of function of the macromolecules.

Education & Training

  • 1988: Columbia University, New York, NY, BA, Pre-Med., Economics
  • 1992: Stanford University, Palo Alto, CA, MD
  • 1994: University of Washington, Seattle, WA, Internal Medicine Residency
  • 1997: Stanford University, Palo Alto, CA, Oncology Fellowship

Awards & Honors

  • 2003: V Foundation Scholar
  • 2002: American Association for Cancer Research Scholar-in-Training Award
  • 1997: American Association for Cancer Research AFLAC Award; American Cancer Society Post-Doctoral Fellowship Award; American Society of Clinical Oncology Young Investigator Award
  • 1993: Alpha Omega Alpha
  • 1990: Stanford Alumni Medical Scholar

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