Jimmy Ye, PhD

Jimmie Ye, PhD, received his bachelor’s degrees in Electrical Engineering and Computer Sciences and Bioengineering from UC Berkeley and a PhD in Systems Biology from UC San Diego.

Following a postdoctoral fellowship at the Broad Institute with Aviv Regev, PhD, Dr. Ye established his lab at UCSF. He is currently an Associate Professor in the Department of Medicine and a member of the Institute for Human Genetics, the Bakar Institute for Computational Health Sciences, and the Gladstone Institute for Genomic Immunology. He is also an affiliated investigator at PICI and the Chan Zuckerberg Biohub.

The Ye Lab investigates how genetic variants influence transcriptional responses of immune cells to their environment. His team develops experimental and computational methods for high-throughput single-cell gene expression analysis across population cohorts, perturbational screens, and tissue regions—applying these approaches to study immune responses in health and disease, including host-pathogen interaction, autoimmunity, and cancer immunity.