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Jim Wells, PhD

Jim Wells, PhD

Professor and Chair of Pharmaceutical Chemistry


James (Jim) Wells is a professor at the UCSF Helen Diller Family Comprehensive Cancer Center and is the chair of Pharmaceutical Chemistry. Wells focuses on understanding and modulating signaling processes in human cells through protein and small molecule design. His lab seeks activators as well as inhibitors of signaling molecules, including proteases and kinases, and uses them to study the consequences of triggering specific nodes of signaling circuits. He is especially interested in the inter-protein circuitry of pathways involved in cell death and inflammation and the intra-protein allosteric circuitry that governs how distant functional sites in one protein communicate.

Education & Training

1973: University of California, Berkeley, CA, BA, Biochemistry 1979: Washington State University, WA, PhD, Biochemistry 1980: Washington State University, WA, Postdoc, Chemistry 1982: Stanford University Medical School, CA, Postdoc, Biochemistry

Awards & Honors

1998: Vincent du Vignead Award, American Peptide Society 1998: Christian B. Anfinsin Award, Protein Society 1990: Pfizer Award (given by the American Chemical Society for achievements in enzyme chemistry) 1981: Damon M. Runyon - Walter Winchell Postdoctoral Fellowship

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