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Evan Weber, PhD

Parker Bridge Fellow


Evan W. Weber, PhD, is a Parker Bridge Fellow and an assistant professor of pediatrics at the University of Pennsylvania Perelman School of Medicine. He received his BS from the University of Michigan and his PhD in Immunology from Northwestern University Feinberg School of Medicine, where he conducted his thesis research under the tutelage of Dr. William Muller, studying the molecular mechanisms by which circulating leukocytes migrate out of the blood vessel during inflammation.

In 2016, Weber joined the laboratory of Crystal Mackall, MD, at Stanford University, as a postdoctoral fellow, where he developed expertise in cancer immunotherapy, CAR-T cell engineering, genomics and T cell exhaustion. His postdoctoral work led to several discoveries, including the identification of small molecule drugs that can control CAR-T cell activity and that providing “rest” to exhausted CAR-T cells rescues their function through epigenetic remodeling. Weber’s current research aims to understand the transcriptional and epigenetic mechanisms that drive CAR-T cell exhaustion in cancer patients and develop universal strategies to enhance CAR-T cell therapeutics by manipulating the epigenome.

Education & Training

  • 2016: Northwestern University, Feinberg School of Medicine PhD, Driskill Graduate Program, Immunology Track
  • 2015: Northwestern University, Kellogg School of Business Certificate in Management for Scientists and Engineers
  • 2008: University of Michigan, College of Literature, Science, and the Arts B.S., Program in the Environment (PITE)

Awards & Honors

  • 2021: Parker Bridge Fellow
  • 2020: First-author paper selected by Blood Advances as “Top Influential Article”
  • 2019: First place award, Immuno-oncology Young Investigators’ Forum (by SITC) – Houston, TX
  • 2015: Outstanding poster award, PISA – Baltimore, MD
  • 2015: American Society for Investigative Pathology Trainee Travel Award
  • 2014: Driskill Graduate Program Travel Award
  • 2014: Northwestern University TGS Travel Grant
  • 2013: American Society for Investigative Pathology Trainee Travel Award