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Parker Institute for Cancer Immunotherapy
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Dana Pe’er, PhD

Scientific Director, GMTEC; Chair, Computational and Systems Biology Program, SKI


The Pe’er lab combines single cell technologies, genomic datasets and machine learning algorithms to address fundamental questions in biomedical science. Empowered by recent breakthrough technologies like massive parallel single cell RNA-sequencing, we ask questions such as: How do multi-cellular organisms develop from a single cell, resulting in the vast diversity of progenitor and terminal cell types? How does a cell’s regulatory circuit control the dynamics of signal processing and how do these circuits rewire over the course of development? How does an ensemble of cells function together to execute a multi-cellular response, such as an immune response to pathogen or cancer? We will also address more medically oriented questions such as: How do regulatory circuits go awry in disease? What is the consequence of intra-tumor heterogeneity? Can we characterize the tumor immune eco-system to gain a better understanding of when or why immunotherapy works or does not work? A key goal is to use this characterization of the tumor immune eco-system to personalize immunotherapy.

Education & Training

  • 1995: Hebrew University of Jerusalem, BA
  • 1999: Hebrew University of Jerusalem, MA
  • 2003: Hebrew University of Jerusalem, PhD, Computer Science
  • Postdoctoral Fellow, Harvard Medical School, Department of Genetics lab of George M. Church

Awards & Honors

  • 2014 NIH Director’s Pioneer Award
  • 2014 ISCB Overton Prize
  • 2012 RECOMB 2012 Test of Time Award
  • 2010 SU2C AACR Innovator award
  • 2009 Packard Fellowship in Science and Engineering
  • 2007 NIH Directors New Innovator Award
  • 2005 Runner up for “Breakthrough of the year”, Science Magazine
  • 2005 Career Award at the Interface of Science, Burroughs Welcome Fund