Catherine J. Wu, MD

Catherine J. Wu, MD, is a physician-scientist at Dana-Farber Cancer Institute and professor of medicine at Harvard Medical School.

She earned her medical degree from Stanford University School of Medicine and completed her clinical training in Internal Medicine and Hematology-Oncology at the Brigham and Women’s Hospital and Dana-Farber. She joined the faculty at Dana-Farber in 2000.

At Dana-Farber, she has initiated an integrated program of research and clinical activities which focuses on dissecting the underlying mechanisms of pathobiology of chronic lymphocytic leukemia (CLL) as a means to generate more effective therapies, including immune-based treatments, for this common adult leukemia. She has been principal investigator of several center-initiated clinical trials, including trials of the NeoVax personalized antigen vaccine.

A major priority of her studies is the identification of tumor-specific antigens that would allow effective tumor targeting without collateral toxicity. She has been using exome and transcriptome sequencing technologies to identify unique mutated tumor antigens that arise from individual-specific genetic alterations within a tumor. The hope is that these could be potentially immunotherapy targets, and could pave the way for developing personalized tumor vaccines.

• Stanford University School of Medicine, CA, MD
• Dana-Farber/Partners CancerCare, Fellowship, Hematology & Oncology
• Brigham and Women's Hospital, Internal Medicine
• Board Certification, Internal Medicine, 1997
• Board Certification, Medical Oncology, 2001
• Board Certification, Internal Medicine, 1997