Carl June, MD Director of the PICI Center at Penn Biography Carl H. June, MD, is the Richard W. Vague Professor in Immunotherapy in the Department of Pathology and Laboratory Medicine and Director of the PICI Center at the University of Pennsylvania. He is also currently Director of the Center for Cellular Immunotherapies at the Perelman School of Medicine. He maintains a research laboratory that studies various mechanisms of lymphocyte activation that relate to immune tolerance and adoptive immunotherapy for cancer and chronic infection. Dr. June has published more than 500 manuscripts and is the recipient of numerous prizes and honors, including election to the Institute of Medicine, the National Academy of Sciences and the American Academy of Arts and Sciences. He recently received the Breakthrough Prize and was a 2024 recipient of the Warren Alpert Foundation Prize for his pioneering work on CAR T-cell therapy, which has saved the lives of tens of thousands of adults and children with blood cancers. Education & Training 1975: United States Naval Academy, BS 1979: Baylor College of Medicine, MD Awards & Honors 2015: Watanabe Prize for Translational Research, Indiana University and Eli Lilly; E. Donnall Thomas Award Lecture, American Society for Blood and Marrow Transplantation; Debrecen Award for Molecular Medicine, University of Debrecen; Lifetime Achievement Award Lecture, Miami Winter Symposium; Paul Ehrlich and Ludwig Darmstaedter Prize; American Academy of Arts and Sciences 2014: Steinman Award for Human Immunology Research, American Association of Immunologists; Elected to American Academy of Arts & Sciences; Hamdan Award for Medical Research Excellence; Taubman Prize for Excellence in Translational Medical Science; Karl Landsteiner Memorial Award, AABB; Aubrey Evans Award, Ronald McDonald House 2013: Richard V Smalley Award, Society for Immunotherapy of Cancer; Philadelphia Award 2012: Earnest Beutler Lecture and Prize, American Society of Hematology; Top 10 Clinical Research Achievement Award, Clinical Research Forum; Elected to Institute of Medicine 2009: Bristol-Myers Squibb Freedom to Discover Award 2006: American Association of Physicians; American Society for Clinical Investigation 2005: Federal Laboratory Award for Excellence in Technology Transfer 2002: William Osler Award, University of Pennsylvania School of Medicine; Lifetime Achievement Award, Leukemia and Lymphoma Society of America 2001: Burroughs Wellcome Fund Award: visiting professor in the basic medical sciences 1997: Frank Brown Berry Prize in Federal Medicine 1996: Dexter Conrad Award, Office of Naval Research, Navy’s highest award for Scientific Achievement; Legion of Merit, US Navy 1992: American Federation for Clinical Research 1991: Fellow, American College of Physicians 1978: Alpha Omega Alpha Medical Society; Michael E. DeBakey Scholar award for the Outstanding Medical Student, Baylor College of Medicine