Jaclyn Lyman, MSc Clinical Scientist Clinical Development Biography Jaclyn Lyman, MSc, has been with PICI since early 2017. She has 9 years of experience in the execution of oncology clinical trials and has pursued educational and professional opportunities in both the United States and United Kingdom throughout her career. Lyman holds a master’s of science in integrated immunology from the University of Oxford and a bachelor’s of arts in molecular biology from Goucher College. Prior to joining PICI, Lyman was at Memorial Sloan Kettering Cancer Center (MSKCC) where she managed the breast cancer trial team and ensured the integrity of more than 50 Phase I-III trials. During her time at MSKCC, she also executed TBCRC013, the Department of Surgery’s first multicenter trial, and played a critical role in developing more efficient departmental processes. As lead for the PICI0002 (PRINCE) trial in advanced pancreatic cancer, Lyman worked with the team to build the infrastructure to support PICI’s first IND filing and opened the clinical trial to enrollment within 4 months of attaining an active IND. PRINCE successfully transitioned to Phase II within 1 year of first patient enrolled, with study enrollment coming to completion in under 2 years. She currently serves as the clinical scientist leading PICI’s expanding pancreatic cancer program, collaborating with academic and industry partners to build off the promise of PRINCE to develop science-driven, clinical trial combinations combating the deadly disease.