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Parker Institute for Cancer Immunotherapy
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Jaclyn Lyman, MSc

Director, Clinical Science and Pancreatic Cancer Programs

Clinical Development


Jaclyn Lyman has been with PICI since early 2017. She has over 10 years experience in the execution of oncology clinical trials and has pursued educational and professional opportunities in both the United States and United Kingdom. Lyman holds a master’s of science in integrated immunology from the University of Oxford and a bachelor’s of arts in molecular biology from Goucher College.

Prior to joining PICI, Lyman was at Memorial Sloan Kettering Cancer Center where she managed the breast cancer trial team and ensured the integrity of more than 50 Phase I-III trials. During her time there, she also executed TBCRC013, the Department of Surgery’s first multi-center trial, and played a critical role in developing cross-departmental processes to support the center’s portfolio of complex and early-phase clinical trials.

As lead for the PICI0002 (PRINCE) trial in advanced pancreatic cancer, Lyman worked with the team to build the infrastructure to support PICI’s first IND filing and opened the clinical trial to enrollment within 4 months of attaining an active IND. PRINCE successfully transitioned to Phase II within 1 year of first patient enrolled, with study enrollment coming to completion in under 2 years. She currently serves as the Director of Clinical Science and Pancreatic Cancer Programs, leading PICI’s expanding pancreatic efforts, collaborating with academic, non-profit and industry partners to build off the promise of PRINCE and develop novel, science-driven approaches of combating the deadly disease.