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Kristin Shotts, PhD

Senior Translational Scientist

Translational and Regulatory

Biography

Kristin Shotts, PhD, serves as a senior translational scientist on the Translational Medicine and Regulatory Affairs team. She works closely with the bioinformatics team to analyze various types of peripheral blood and tumor derived biomarker data, which is collected from patients in PICI’s oncology clinical trials. The end goal is to characterize the immune landscape and tumor microenvironment in our patients to assess the correlates of clinical response and guide patient selection for future trials.

Shotts was most recently a process development scientist at Atara Biotherapeutics where she developed spectral flow based assays to characterize and optimize CAR-T cell culturing and phenotyping for their allogeneic cell therapy platform. Shotts has 7 years of oncology industry experience and has worked on various drug types including immunotherapy, small molecule inhibitors, RNA based therapeutics and adoptive cell therapy. Shotts has vast experience in the translational science field from developing tumor based imaging (IHC/IF) assays at Flagship Biosciences and analyzing clinical trial biomarker data at miRagen (now Viridian) Therapeutics. She also has mass spectrometry and drug metabolism experience from working with small molecule inhibitors at Array BioPharma (now Pfizer) prior to graduate school.

Shotts received her PhD from the University of Colorado, Anschutz Medical Campus, in 2016 and performed her thesis work in the Torres lab, focusing on the cross-reactive antibody response to HIV-1 from autoimmune individuals. She received her bachelors degree from the University of Colorado, Boulder, in 2008 in biochemistry and molecular biology.