The quest towards defeating cancer is shaped by a diversity of approaches, represented by paths converging towards the common goal. The sparse early inroads have more recently given way to a robust network of strategies uncovering and targeting cancer vulnerabilities, which have been boosted by technological advances, joint effort from an expanded research community, and integration of basic and clinical science.
Many of our Parker Institute members have been featured in this issue of Cell. Here are a few of their articles:
- The Principles of Engineering Immune Cells to Treat Cancer - Wendell A. Lim, Carl H. June
- Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy - Padmanee Sharma, Siwen Hu-Lieskovan, Jennifer A. Wargo, Antoni Ribas
- Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer - Juan R. Cubillos-Ruiz, Sarah E. Bettigole, Laurie H. Glimcher